FSH Followed by HMG vs FSH Plus HMG in IVF

• Status: Recruiting
• Trial end date: 2022-08-31
• Target enrollment: 0
• Participant gender: Female

Summary

The aim of this study is to compare the clinical outcomes of sequential administration of FSH and HP-hMG FSH alone versus concomitant administration of FSH and HP-hMG during controlled ovarian stimulation in IVF cycles.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Mansoura University
• Treatments: Menotropins

Criteria

Inclusion Criteria:

• Women who are planned to be subjected to IVF/ICSI through COS by long GnRHa protocol.

• Women with regular menstrual cycle (21-35 days) and normal uterine anatomy (confirmed by transvaginal ultrasound examination and in some cases hysteronsalpingography and hysteroscopy).

Exclusion Criteria:

• Age < 20 or > 37 years.

• Body mass index (BMI) < 18 or > 30 kg/m2.

• Low ovarian reserve (AFC < 7 and/or AMH < 1.1 ng/ml).

• Presence of polycystic ovarian syndrome (PCOS).

• Endometrioma or hydrosalpinx.

• History of chemotherapy, radiotherapy or ovarian surgery.

• The husband needs testicular biopsy to obtain sperm.

• Previous implantation failure.