This project will collect quantitative pilot data that will allow the characterization of
uptake and binding of 18F-AV-1451 (also known as F 18 T807), a novel tau imaging compound, in
individuals with and without brain tau fibrils. The primary goal is to develop tau imaging
technique as an antecedent biomarker of cognitive decline. The investigators propose to
obtain preliminary data that will support the possibility of detecting cognitive decline in
its earliest stages, before the occurrence of dementia.
Details
Lead Sponsor:
Tammie L. S. Benzinger, MD, PhD Washington University School of Medicine