Ezetimibe Versus Nutraceuticals in Statin-intolerant Patients

• Status: Unknown status
• Trial end date: 2016-12-01
• Target enrollment: 0
• Participant gender: All

Summary

Pharmacologic alternatives in statin-intolerant patients include ezetimibe and nutraceuticals (i.e. compounds derived from foods with cholesterol lowering actions). The investigators will compare the efficacy and tolerability of ezetimibe versus a nutraceutical-based protocol in statin-intolerant patients treated with percutaneous coronary intervention.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Roma La Sapienza
• Treatments: Ezetimibe; Red yeast rice

Criteria

Inclusion Criteria:

• Angiographically-proven coronary artery disease

• Recent (< 12 months) percutaneous coronary intervention

• Class I indication to receive statin treatment

• Previous (< 12 months) withdrawn of a statin due to side effects

• Unwilling to receive treatment with an alternative statin

• Able to understand and willing to sign the informed consent form

Exclusion Criteria:

• Women of child bearing potential patients must demonstrate a negative pregnancy test performed within 24 hours before