Extragonadal Effects of hCG on Calcium Homeostasis

• Status: Active, not recruiting
• Trial end date: 2021-12-31
• Target enrollment: 0
• Participant gender: Male

Summary

A pilot study showed that serum calcium levels and calcium homeostasis change in response to hCG stimulation test. Serum calcium level differed when comparing pretreatment values at baseline with serum levels 72 hours after hCG stimulation in men with gonadal insufficiency referred for this stimulation test. Now we want to investigate whether this change in calcium is due to renal loss or other mechanisms and how the classical regulators of calcium homeostasis respond to hCG in men with impaired gonadal function compared with men having normal gonadal function. Moreover, the observed change in serum calcium implies that hCG also changes Phosphate, PTH and calcitonin and this will be clarified with this study

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Martin Blomberg Jensen
• Treatments: Chorionic Gonadotropin

Criteria

Inclusion Criteria: to be either

• a man with normal reproductive function

• or a man with known impaired gonadal function

• more than 18 years of age and less than 80 years of age

Exclusion Criteria:

• presence of current serious diseases

• or presence of disease requiring constant and lifelong treatment with chemotherapy or other toxic drugs

• Men treated with testosterone who do not stop their treatment while being part of the study,