Extragonadal Effects of hCG on Calcium Homeostasis
Status:
Active, not recruiting
Trial end date:
2021-12-31
Target enrollment:
Participant gender:
Summary
A pilot study showed that serum calcium levels and calcium homeostasis change in response to
hCG stimulation test. Serum calcium level differed when comparing pretreatment values at
baseline with serum levels 72 hours after hCG stimulation in men with gonadal insufficiency
referred for this stimulation test. Now we want to investigate whether this change in calcium
is due to renal loss or other mechanisms and how the classical regulators of calcium
homeostasis respond to hCG in men with impaired gonadal function compared with men having
normal gonadal function. Moreover, the observed change in serum calcium implies that hCG also
changes Phosphate, PTH and calcitonin and this will be clarified with this study