Extended Release Naltrexone for Treating Amphetamine Dependence in Iceland
Status:
Completed
Trial end date:
2013-02-01
Target enrollment:
Participant gender:
Summary
Until positive results were found with oral naltrexone, no medication has been effective
against amphetamine dependence. The primary aim of this pilot study is to replicate the
findings of the Swedish team that showed oral Naltrexone prevented relapse to amphetamine
addiction and to extend their results by randomizing treatment-seeking amphetamine addicted
patients to a 6 month course of VIVITROL (naltrexone for extended-release injectable
suspension) or VIVITROL placebo. Patients in each group will receive drug counseling.
VIVITROL is administered monthly and may be a better test of efficacy than tablets that must
be taken daily.
Phase:
Phase 3
Details
Lead Sponsor:
University of Pennsylvania
Collaborators:
National Institute on Drug Abuse (NIDA) Society of Alcoholism and other Addictions