Extended Release Local Anesthetic for Postsurgical Pain After Posterior Colporrhaphy and Perineorrhaphy
Status:
Completed
Trial end date:
2019-03-31
Target enrollment:
Participant gender:
Summary
The specific aim of this randomized double-blind clinical trial is to evaluate the effect of
intraoperative infiltration of liposomal bupivacaine at the time of posterior colporrhaphy
and/or perineorrhaphy on postsurgical pain scores during the first 72 hours after surgery as
measured by visual analog scales (VAS) for patients undergoing surgery for pelvic organ
prolapse. Study subjects are randomized to 30 mL of liposomal bupivacaine versus 30 mL of
injectable normal saline administered in a standardized technique into the posterior vaginal
compartment at the time of posterior repair and/or perineorrhaphy.