Overview

Extended Letrozole Regimen Co-treatment With Gonadotropin Releasing Hormone Antagonist Protocol Versus Gonadotropin Releasing Hormone Antagonist Protocol in Poor Responders Undergoing IVF-ET

Status:
Recruiting
Trial end date:
2020-04-20
Target enrollment:
0
Participant gender:
Female
Summary
The object of this study is to evaluate the efficacy of extended letrozole co-treatment with GnRH-antagonist protocol in ovarian stimulation of poor responder patients undergoing IVF-ET.
Phase:
Phase 2
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Cairo University
Treatments:
Cetrorelix
Estradiol
Estradiol 17 beta-cypionate
Estradiol 3-benzoate
Hormone Antagonists
Hormones
Letrozole
LHRH, N-acetyl-(4-chlorophenylalanyl)(1)-(4-chlorophenylalanyl)(2)-tryptophyl(3)-arginyl(6)-alanine(10)-
Polyestradiol phosphate
Prolactin Release-Inhibiting Factors
Criteria
Inclusion Criteria:

- Poor responders according to the ESHRE Bologna criteria

Exclusion Criteria:

Age > 42 years FSH> 12 IU/L Irregular menstrual cycles Unilateral ovary Polycystic ovary
syndrome Endometriosis Male factor of infertility requiring ICSI History of recurrent
miscarriage Endocrinologic disorders Systemic disease contraindicating pregnancy