Exploring the Impact of Perioperative Galacto-Oligosaccharides (GOS) on Stress, Anxiety and Cognition
Status:
Withdrawn
Trial end date:
2018-01-01
Target enrollment:
Participant gender:
Summary
The overall objective of this proposal is to explore the association between the
administration of the prebiotics GOS (trade name: Bimuno Travelaid; generic name:B
galacto-oligosaccharides) with pain, anxiety, and cognitive function in the perioperative
period. The investigators' central hypothesis is subjects who consume GOS in the
perioperative period will demonstrate lower levels of salivary cortisol before, during, and
after their operative procedures. In addition, the investigators expect subjects who consume
GOS to have lower perceived levels of anxiety during the perioperative period. Finally, the
investigators hypothesize that subjects who consume perioperative GOS will perform better on
tests of cognition in the postoperative period. Such a finding would be beneficial in that
administration of GOS in the perioperative period offers a safe and inexpensive adjunct to
current medical management of perioperative anxiety.