Exploring the Effect of Lactate Administration After Ischemic Stroke on Brain Metabolism
Status:
Recruiting
Trial end date:
2024-03-01
Target enrollment:
Participant gender:
Summary
In this exploratory randomized double blind placebo controled trial, lactate solution or
placebo will be administered to acute ischemic stroke patients selected for endovascular
treatment (EVT) without intravenous thrombolysis. The treatment will be administered within
one hour after EVT. Primary outcome measures will be lactate and metabolite concentrations in
the ischemic lesion, in the penumbra and contralaterally, evaluated by magnetic resonance
spectroscopy(MRS). Secondary outcome measures will be evolution of the ischemic penumbra,
clinical outcome at 3 months.The trial will end when 10 patients per group have completed the
study.