Explore the Clinical Application Value of Ciprofol in Painless Colonoscopy

• Status: Not yet recruiting
• Trial end date: 2022-12-31
• Target enrollment: 0
• Participant gender: All

Summary

This study used propofol as a positive control, and adopted a large-sample, multi-center, randomized, double-blind, positive parallel controlled trial design to explore the clinical application value of ciprofol in painless colonoscopy.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Sichuan Provincial People's Hospital
• Treatments: Propofol

Criteria

Inclusion Criteria:

1. Patients undergoing painless colonoscopy;

2. Patients aged from 18 to 80 years old, no gender limitation; 3, 18 < BMI < 30kg/m2 [BMI = weight (kg)/ height (m) squared]

4. American Society of Anesthesiologists (ASA) grades ⅰ ~ ⅲ

Exclusion Criteria:

1. Preoperative blood pressure >160/100 mmHG or < 80/50 mmHG.

2. Preoperative ecg suggested heart rate <50 times/min;

3. Acute respiratory tract infection with no cured history within 2 weeks;

4. People with serious metabolic diseases such as heart, brain, lung, liver, kidney and diabetes;

5. Predict people who may have or have had difficult airway;

6. Patients with obvious electrolyte disorders such as hyperkalemia;

7. Long-term use of immunosuppressants such as hormones or history of adrenocortical inhibition;

8. People who are known to be allergic to emulsions and opioids;

9. Preoperative combined use of other sedative and analgesic drugs

10. Suspected abuse of narcotic analgesics or sedatives; 11, there are neuromuscular system diseases, mental diseases and other people do not cooperate with the communication;