Exploratory fMRI Study on the Treatment for Impulsive Aggression in Children With ADHD
Status:
Terminated
Trial end date:
2019-11-07
Target enrollment:
Participant gender:
Summary
The purpose of this study is to evaluate the effect of 4-week SPN-810 treatment on brain
functioning in patients aged 8-12 years with ADHD and associated feature of IA. This will be
achieved using functional magnetic resonance imaging (fMRI) in conjunction with the point
subtraction aggression paradigm (PSAP) Task, a behavioral aggression paradigm in which
subjects are provoked by having money indirectly taken from them by a fictitious opponent,
simulating an aggression response.