Exploratory Study to Evaluate the Effects of the Probiotics L. Rhamnosus GR-1 and L. Reuteri RC-14
Status:
Completed
Trial end date:
2013-05-01
Target enrollment:
Participant gender:
Summary
The purpose of this study was to determine whether L. rhamnosus GR-1 and L. reuteri RC-14
delivered via capsules to the vagina of post-menopausal women over a three day course of
treatment can restore and maintain a lactobacilli-dominated microbiota. Exploratory analysis
of microbial ecology, human microarrays and multiplex immunological assessments are included
to characterize potential effects.
Phase:
Early Phase 1
Details
Lead Sponsor:
Kimberly-Clark Corporation
Collaborators:
Integrated Research Inc. Lawson Health Research Institute Western University, Canada