Overview Exercise and Olanzapine-samidorphan Status: RECRUITING Trial end date: 2027-04-01 Target enrollment: Participant gender: Summary This is a single site trial in 30 patients with schizophrenia, schizoaffective, or bipolar I/II/NOS disorder in which all participants will receive eight weeks of olanzapine and samidorphan (Olz/Sam) plus four weeks of aerobic exercise.Phase: PHASE4 Details Lead Sponsor: New York State Psychiatric InstituteTreatments: Exercise