Overview

Examination of the Metabolic Effects of Direct Bile Salt Delivery to the Ileum in Humans

Status:
Terminated
Trial end date:
2020-05-01
Target enrollment:
Participant gender:
Summary
This project will evaluate distal intestinal bile salt administration in humans by deliving ursodeoxycholic acid (UDCA) into the terminal ileum of subjects with a pre-existing ileostomy and assessing several hormone levels following an oral glucose tolerance test compared to a placebo.
Phase:
Phase 1
Details
Lead Sponsor:
Vanderbilt University Medical Center
Treatments:
Bile Acids and Salts
Ursodeoxycholic Acid