Overview

Evolutionary Therapy for Rhabdomyosarcoma

Status:
Recruiting
Trial end date:
2027-12-01
Target enrollment:
Participant gender:
Summary
This clinical trial will evaluate 4 different strategies of chemotherapy schedules in newly diagnosed participants with metastatic Fusion Positive (alveolar) Rhabdomyosarcoma. The participant and their physician will choose from: Arm A) a first strike therapy, Arm B) a first strike-second strike (maintenance) therapy, Arm C) an adaptively timed therapy, and Arm D) conventional chemotherapy.
Phase:
Phase 2
Details
Lead Sponsor:
H. Lee Moffitt Cancer Center and Research Institute
Collaborator:
National Pediatric Cancer Foundation
Treatments:
Cyclophosphamide
Dactinomycin
Vincristine
Vinorelbine