Evidence of Spreading Vasoconstriction in Human Gingiva

• Status: Completed
• Trial end date: 2020-01-01
• Target enrollment: 0
• Participant gender: All

Summary

The aim of this study is to observe the mechanism of spreading vasoconstriction in human healthy gingiva. Epinephrine solution is applied on the attached gingiva in group "A" and on the surface of the tooth next to the ginvial sulcus in group "B". The different placement of the solution causes different effect in the microcirculation.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Semmelweis University
• Treatments: Epinephrine; Epinephryl borate; Racepinephrine

Criteria

Inclusion Criteria:

• at least 5 mm keratinized gingiva at the upper front teeth

• general health

Exclusion Criteria:

• pregnancy, breast-feeding

• any medication

• smoking, gingivitis, caries and coronal restoration with insufficient marginal integrity