Evidence-Based Evaluation of Classic Herb Pair (Chuanxiong Rhizoma and Salviae Miltiorrhizae) for Preventing Recurrence of Diabetic Lower Extremity Arterial Disease

• Status: NOT_YET_RECRUITING
• Trial end date: 2028-12-01

Summary

Taking the approach of promoting qi circulation and activating blood as the entry point, this study targets lower extremity arterial diseaseLEAD patients with TCM syndrome pattern of blood stasis due to qi stagnation. Using Guanxinning Tablets (a herbal formula with qi-moving and blood-activating properties) as the investigational medication, we will conduct a multicenter, randomized, double-blind, placebo-controlled clinical trial to evaluate the efficacy and safety of the classic herb pair (Chuanxiong Rhizoma-Salviae Miltiorrhizae) in preventing LEAD ulcer recurrence. This research aims to accumulate evidence-based medical data supporting new drug development.

• Phase: EARLY_PHASE1

Details

• Lead Sponsor: Zheng Liu
• Collaborators: Beijing Shijitan Hospital, Capital Medical University; Dongzhimen Hospital, Beijing; Liyuan Hospital of Tongji Medical College, Huazhong University of Science and Technology; Peking University Third Hospital; The First Affiliated Hospital, Guangzhou University of Traditional Chinese Medicine; Xuanwu Hospital, Beijing