Everolimus and Whole-Brain Radiation Therapy in Treating Patients With Brain Metastasis From Non-Small Cell Lung Cancer
Status:
Terminated
Trial end date:
2011-02-01
Target enrollment:
Participant gender:
Summary
RATIONALE: Everolimus may stop the growth of tumor cells by blocking some of the enzymes
needed for cell growth and by blocking blood flow to the tumor. Radiation therapy uses
high-energy x-rays to kill tumor cells. Giving everolimus together with whole-brain radiation
therapy may kill more tumor cells.
PURPOSE: This phase I/II trial is studying the side effects and best dose of everolimus and
to see how well it works when given together with whole-brain radiation therapy in treating
patients with brain metastasis from non-small cell lung cancer.