Overview

Evaluation of the Simplified Treat And Extend Regimen Using Ranibizumab in Exudative Age Related Macular Degeneration

Status:
Unknown status
Trial end date:
2016-12-01
Target enrollment:
0
Participant gender:
All
Summary
Recently studies have shown that intravitreal injection of ranibizumab is effective for age related macular degeneration. However there are problems about injection regimen of maintenance phase. We plan to perform new simplified treat and extend regimen using ranibizumab.
Phase:
N/A
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Mie University
Treatments:
Ranibizumab
Criteria
Inclusion Criteria:

1. ability to provide written informed consent for this study

2. age>=50years old

3. intravitreal injection of ranibizumab as a first therapy for neovascular age-related
macular degeneration (typical age-related macular degeneration and PCV)

4. best corrected visual acuity>=0.05 -

Exclusion Criteria:

1. past intravitreal anti-vascular endothelial growth factor therapy in the study eye

2. past intravitreal or subtenon injection of steroid therapy in the study eye

3. past vitrectomy therapy in the study eye

4. infection or suspicion of infection in eyes or periocular region

5. severe intraocular inflammation in eyes

6. past allergic reaction for ranibizumab

7. past allergic reaction for fluorescein, indocyanine green or iodine

8. pregnancy (positive pregnancy test) or lactating women

9. other conditions that the investigator believed would pose a significant hazard to the
subject if investigational therapy were initiated.