Overview

Evaluation of the Safety and Pharmacology of EYP001 in HBV Subjects

Status:
Completed
Trial end date:
2018-07-30
Target enrollment:
Participant gender:
Summary
Bile acids regulating farnesoid X receptor (FXR) interact with hepatitis B virus replication. EYP001a is a selective, synthetic FXR agonist under development for the treatment of hepatitis B. This Phase 1b study is designed primarily to determine the safety, tolerability, pharmacokinetics and pharmacodynamics of EYP001a in chronically HBV infected subjects.
Phase:
Phase 1
Details
Lead Sponsor:
Enyo Pharma
Collaborator:
CPR Pharma Services Pty Ltd, Australia
Treatments:
Entecavir
Interferon alpha-2
Interferon-alpha
Interferons
Peginterferon alfa-2a