Overview Evaluation of the Metabolic Effects of LCZ696 and Amlodipine in Obese Hypertensive Subjects Status: Completed Trial end date: 2013-07-01 Target enrollment: Participant gender: Summary This study investigated the effects of LCZ696 on insulin sensitivity, lipolysis, and oxidative metabolism in obese hypertensive subjects. Phase: Phase 2 Details Lead Sponsor: Novartis PharmaceuticalsTreatments: AmlodipineLCZ 696Sacubitril and valsartan sodium hydrate drug combination