Evaluation of the Efficacy of Captopril Versus Propranolol and Timolol as a Treatment of Infantile Capillary Hemangioma

• Status: Recruiting
• Trial end date: 2021-10-01
• Target enrollment: 0
• Participant gender: All

Summary

Is to compare and evaluate the efficacy of oral captopril with oral propranolol, intralesional propranolol injection, and topical Timolol in the treatment of infantile hemangioma and their effect on vascular endothelial growth factor and CD 133.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Ain Shams University
• Treatments: Captopril; Ophthalmic Solutions; Propranolol; Timolol

Criteria

Inclusion Criteria:

• Pediatric patients younger than 12 years and older than 2 months of age with infantile hemangioma

Exclusion Criteria:

• Patient with ulcerated or infected hemangioma.

• Patient younger than 2 months and older than 12 years of age.

• Patients with multiple hemangiomas.

• Any Patient with cardiovascular problems, bronchial asthma, diabetes mellitus, bilateral renal stenosis, Electrolyte disturbance, or renal impairment was excluded.

• Patients with abnormal electrocardiogram, or echocardiogram should be excluded.

• Patients who have had previous treatment for hemangioma.