Evaluation of the Effectiveness of Topiramate in Preventing the Transformation From Episodic Migraine to Chronic Daily Headache.

• Status: Completed
• Trial end date: 2007-08-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine whether Topiramate is effective in preventing the development of chronic daily headache among patients with episodic migraine headaches.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Ortho-McNeil Neurologics, Inc.
• Treatments: Topiramate

Criteria

Inclusion Criteria:

• To qualify for this study you must be 18-65 years old

• have a history of migraine headaches for at least 1 year

• experience at least 10 but less than 15 migraine headache days and less than 15 total headache days/month

• able to take oral medication

• able to understand and sign the informed consent and to complete headache diaries.

Exclusion Criteria:

• You will not be able to participate in the study if you previously discontinued Topiramate because it did not make you feel better or it made you feel different

• have migraine aura without headache

• have a positive urine drug screen

• have a history of kidney stones

• have a history of suicide attempt

• pregnant females

• already on a migraine preventive medicine.