Evaluation of the Effect of Different Doses Dexmedetomidine Infusion on Lung Mechanics and Oxygenation in Obese Patients

• Status: Recruiting
• Trial end date: 2021-06-01
• Target enrollment: 0
• Participant gender: All

Summary

• The objective of this study is to evaluate the effect of different doses of dexmedetomidine infusion intraoperative on lung mechanics and oxygenation regarding PaO2/Fraction of inspired oxygen), Intraoperative oxygenation, lung compliance (static and dynamic), dead space, and PaCO2,heart rate, mean arterial blood pressure in obese patients undergoing laparoscopic cancer surgeries

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: National Cancer Institute, Egypt
• Treatments: Dexmedetomidine

Criteria

Inclusion Criteria:

• Age 18-60years

• Obese patients BMI>25 Kg/meter square

• Patients undergoing laparoscopic cancer surgery.

Exclusion Criteria:

• Heart failure

• Arrhythmias

• Severe liver or kidney impairment

• Patients with forced expiratory volume in 1 sec (FEV1)/FVC < 70%

• Heart block