Evaluation of an Herbal-Based De-Pigmenting System

• Status: Completed
• Trial end date: 2014-10-01
• Target enrollment: 0
• Participant gender: Female

Summary

The purpose of this study is to evaluate the effectiveness and tolerability of an herbal de-pigmenting regimen applied to one side of the face compared with hydroquinone applied to the other side of the face in treating mottled hyperpigmentation and melasma.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Sadick Research Group
• Collaborator: Episciences, Inc.
• Treatments: Hydroquinone

Criteria

Inclusion Criteria:

• Female age 30-65

• Must be in good general health

• Must be willing to use sunscreen on the face daily

• Must be willing to avoid tanning beds and excessive exposure to direct sunlight

• Must be willing to continue using regular cosmetic regimen

Exclusion Criteria:

• Nursing pregnant/ planning to become pregnant during the course of the study

• Using a medication that increases sensitivity to sunlight including doxycycline, minocycline, tetracycline, ciprofloxin, hydrochlorothiazide, and sulfonamides.

• Any known allergies/sensitivities to facial skincare products, anti-aging products, de-pigmenting products, or products containing hydroquinone

• Usage of any new skincare products during the course of the study

• Presence of atopic dermatitis or psoriasis on the face

• Uncontrolled diabetes, hypertension, hypothyroidism, hyperthyroidism

• TCA or other deep peels within 1 year or medium to light peels within 3 months prior to starting the study

• Facial/laser treatment within the last 3 months

• Facial cosmetic surgery within the last 12 months

• Use of product, topical, or systemic medication, known to affect dyschromia, having "whitening" or anti-aging properties

• Physical skin conditions such as excessive hair, scarring, tattoos that might impair evaluations of the test sites

• Active hepatitis, immune deficiency, or autoimmune disease