Evaluation of Xiaflex: Trial of Effectivenss iN Dupuytren's
Status:
Active, not recruiting
Trial end date:
2021-11-01
Target enrollment:
Participant gender:
Summary
This is a prospective, multi-centre, pragmatic randomized controlled trial to compare both
the clinical effectiveness and cost-effectiveness of collagenase injections (CI) versus
limited palmar fasciectomy (LPF) to determine if collagenase is a superior treatment in terms
of improved quality of life and reducing recurrence of the disease without serious
complications. Since collagenase injections are costly it is also important to know if this
novel intervention is cost-effective from the patient, Ministry of Health and societal
perspectives.