Evaluation of Two Techniques for the SLN Detection in BC Patients
Status:
Unknown status
Trial end date:
2014-12-01
Target enrollment:
Participant gender:
Summary
The revision of our data shows that since its introduction in our institution (Jules Bordet
Institute) in 1998 (until 2010, the year of the last review of cases), 53 patients underwent
neoadjuvant therapy before selective sentinel lymph node dissection followed by conventional
axillary dissection.
The analysis of these cases shows that:
- The lack of demonstration of sentinel lymph nodes observed in 8 cases (6 cN0) is
associated in 75% of them with a pN+ status
- If scintigraphic imaging is "positive" (demonstration of the sentinel lymph nodes: 35
cN0 and 10 cN+), our results appear favorable with a single false negative SLN result
(False Negative Rate = 1/20 or 5%).
Therefore we propose additional technique for LN detection by indocyanine green, we
hypothesize that the combination of two different injections improves the technique of
sentinel lymph node biopsy.