Evaluation of Safety and Efficacy of Remifentanil in Pediatric Population

• Status: Completed
• Trial end date: 2012-04-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to evaluate safety and efficacy of continuous infusion of remifentanil in preterm infant with mechanical ventilator for control of procedural pain using two different dosage of remifentanil.

• Phase: Phase 1/Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Seoul National University Hospital
• Collaborators: Ajou University School of Medicine; Severance Hospital
• Treatments: Remifentanil

Criteria

Inclusion Criteria:

• preterm infants mechanically ventilated

• requiring peripherally induced central catheterization

• with informed consent of their parents

Exclusion Criteria:

• major congenital anomalies

• cardiopulmonary instability

• use of sedative, antiepileptic drugs or anesthetic drugs

• grade III or IV intraventricular hemorrhage