Evaluation of SP Resistance and Effectiveness of IPTp in Nigeria
Status:
Unknown status
Trial end date:
2013-02-01
Target enrollment:
Participant gender:
Summary
The study has two components: component A is a cohort study to determine the in vivo efficacy
of SP to clear and prevent malaria parasitaemia in asymptomatic pregnant women and component
B is a cross sectional study of women delivering at the study hospitals to assess the
effectiveness of SP-IPTp to reduce adverse maternal and birth outcomes in the current context
of increasing SP resistance. Results of component A and B studies will be used to model the
relationship between the prevalence of molecular markers of SP resistance, in vivo efficacy
to clear parasite and the effectiveness of SP-IPTp and to develop guidelines for routine
monitoring effectiveness of SP-IPTp as part of ANC surveillance.
Phase:
Phase 4
Details
Lead Sponsor:
Malaria Consortium, UK
Collaborators:
Department for International Development, United Kingdom London School of Hygiene and Tropical Medicine University of Nigeria, Enugu Campus
Treatments:
Fanasil, pyrimethamine drug combination Pyrimethamine Sulfadoxine