Evaluation of Rosiglitazone Anti-inflammatory Effect With FDG-PET Imaging
Status:
Completed
Trial end date:
2014-03-01
Target enrollment:
Participant gender:
Summary
The purpose of this research study is to gain understanding of the basic responses of the
lung to inflammation and specifically if a certain medication can reduce the inflammation
alone or in combination with another. Inflammation is the way our bodies react to irritation
or injury, and involves red, warm, and often painful swelling of the affected tissue. "Acute
lung injury" involves inflammation that is not specific to one area of the lung and is caused
by any one of several conditions: infection, trauma, breathing toxic substances, etc. When
lung injury is severe, not enough oxygen can get into the body; this can lead to the need for
mechanical support of breathing (mechanical ventilation), problems with brain, heart or other
organ function, and in some cases, death.