Evaluation of Progression of Myopia in Children Treated With Vitamin B2 and Outdoor Sunlight Exposure

• Status: Recruiting
• Trial end date: 2023-10-10
• Target enrollment: 0
• Participant gender: All

Summary

The investigators plan on using riboflavin (a Vitamin that can easily be taken orally each day) and having the children involved in the study play outside (where there is UV light created by the sun) in order to prevent the eye from becoming progressively more near-sighted.

• Phase: Phase 2
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University of Missouri-Columbia
• Treatments: Riboflavin; Vitamin B Complex; Vitamins

Criteria

Inclusion Criteria:

• Healthy children ages 6-12 years old with myopia more than 0.50 D and astigmatism no more than 1.5 D.

• Caretakers who choose to enroll their child in the study must agree to participate in the study on their own will after knowledge of potential alternatives (spectacle correction, orthokeratology, atropine eye drops, etc.) are explained to the patient's caretaker.

Exclusion Criteria:

• Known allergy to riboflavin

• Birth history of premature birth

• Developmental delay or other neurological or mental conditions

• Major systemic health problems

• Significant anisometropia more than 1.5 Diopters

• Any other eye condition which may complicate interpretation of data including:

congenital glaucoma, congenital cataract, ectatic corneal condition, amblyopia or strabismus.