Evaluation of Preoperative Use of Pregabalin on Postoperative Analgesia After Laparoscopic Colorectal Surgery

• Status: Completed
• Trial end date: 2018-01-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to evaluate how effective is the preoperative administration of pregabalin 300mg, to attenuate postoperative pain and opioids consumption after laparoscopic colorectal surgery

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Larissa University Hospital
• Collaborator: University of Thessaly
• Treatments: Morphine; Pregabalin

Criteria

Inclusion Criteria:

• ASA physical status I-III

• Patients who undergo laparoscopic colectomy for benign or malignant colorectal disease ( <Τ3 or =T3 tumors without distant metastasis )

Exclusion Criteria:

• Contraindication for pneumoperitoneum

• Contraindication for laparoscopic approach

• Renal or hepatic insufficiency

• Alcohol or drugs abuse

• History of chronic pain or daily intake of analgesics

• Psychiatric disorders

• Inability of patients to use PCA pump History of intake of non-steroidal anti-inflammatory drugs the last 24 hours before surgery,use of drainage after the surgery