Overview

Evaluation of Preoperative Submucosal Dexamethasone in Third Molar Surgery

Status:
Completed
Trial end date:
2016-03-01
Target enrollment:
Participant gender:
Summary
The study composed of sixty patients, each of whom required surgical extraction of a single impacted mandibular third molar under local anaesthesia. The patients were randomly allocated to one of 3 groups of 20 each. The three groups were categorized as Group A (intramuscular dexamethasone), Group B (submucosal dexamethasone) and Group C (control). The objective measurements of facial pain, swelling, and trismus was performed by an independent examiner at baseline (preoperatively), and at days 1, 3, and 7 postoperatively.
Phase:
Early Phase 1
Details
Lead Sponsor:
Sun Yat-sen University
Treatments:
Acetaminophen
Amoxicillin
BB 1101
Dexamethasone
Dexamethasone 21-phosphate
Dexamethasone acetate