Evaluation of PrEP-30: a Demonstration Project of Pre-exposure Prophylaxis for MSM and Other High-risk Group Clients at the Thai Red Cross Anonymous Clinic

• Status: Enrolling by invitation
• Trial end date: 2027-01-01
• Target enrollment: 0
• Participant gender: All

Summary

PrEP-30 is a demonstration project to assess the feasibility of providing oral PrEP to MSM and other individuals at-risk for HIV in Bangkok, Thailand as a service that is funded entirely through user fees. Tenofovir disoproxil fumarate/emtricitabine PrEP is provided part of a combined HIV prevention program that includes risk-reduction counseling, regular HIV testing, and the provision of condoms and lubricants. PrEP-30 is implemented at the Thai Red Cross AIDS Research Centre, at the site of the largest HIV counseling and testing center in Thailand.

• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Thai Red Cross AIDS Research Centre

Criteria

Inclusion Criteria:

1. Age > 18 years

2. HIV test negative

3. Creatinine clearance > 60 ml/min

4. No contraindication or allergy to PrEP medications (TDF/FTC)

5. At least one risk factor for HIV infection within the previous 6 months:

• sex partner known to be HIV positive

• works as commercial sex worker

• use of PEP for sexual exposure

• injection drug use

• any STI (syphilis, gonorrhea, chlamydia)

• > 5 sex partners

• inconsistent condom use with high-risk partners, including MSM, IDU

• MSM: any insertive or receptive anal sex without condom

• Women: any sex without condom with high-risk male partner (MSM, IDU, multiple female partners)

• Heterosexual men: any sex without condom with high-risk female partner (commercial sex worker, IDU, multiple male partners)

Exclusion Criteria: -