Overview

Evaluation of Nelfinavir and Chemoradiation for Pancreatic Cancer

Status:
Terminated
Trial end date:
2015-07-01
Target enrollment:
Participant gender:
Summary
This study is designed to evaluate if nelfinavir works as a radiation sensitizer in combination with gemcitabine (a chemotherapy). We are also looking to establish the maximum dose of gemcitabine that is tolerated with the nelfinavir and radiation therapy, so the dose of gemcitabine is increased based on how previous trial participants tolerated their dose of gemcitabine.
Phase:
Phase 1
Details
Lead Sponsor:
University of Iowa
Collaborator:
Holden Comprehensive Cancer Center
Treatments:
Gemcitabine
HIV Protease Inhibitors
Nelfinavir