Evaluation of Naloxegol in the Prevention of POI After Cystectomy
Status:
Not yet recruiting
Trial end date:
2022-12-01
Target enrollment:
Participant gender:
Summary
Postoperative ileus (POI) is defined as a transient reduction of bowel motility that prevents
effective transit of bowel content and tolerance of oral intake following surgical
interventions, especially after radical cystectomy. It remains a major factor associated with
postoperative morbidity, length of hospital stay and medical costs.
In order to optimize perioperative care for patients undergoing radical cystectomy in a
context of an ERAS (Enhanced Recovery After Surgery) program, we will evaluate the
effectiveness of systemic pharmacologic opioid antagonist treatment.