Evaluation of Macular Changes After Intracameral Moxifloxacin for Prevention of Endophthalmitis

• Status: Completed
• Trial end date: 2019-12-30
• Target enrollment: 0
• Participant gender: All

Summary

The objective of this study is to evaluate the macular and choroidal thickness of patients submitted to intracameral moxifloxacin during the phacoemulsification surgery for endophthalmitis prophylaxis.

The investigators propose a randomized clinical trial double-blind. The patients will be divided into two groups: one will receive intracameral moxifloxacin injection during phacoemulsification surgery and the other won't.

Both Spectral Domain - Optical Coherence Tomography (SD-OCT) and Enhanced Depth Imaging - Optical Coherence Tomography (EDI-OCT) will be performed for each patient pre-operatively and on the 30th and 60th postoperative days.

After collecting, the data will be compared to evaluate if there was any difference in the macular thickness and choroidal thickness between the two groups.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Universidade Federal de Pernambuco
• Treatments: Moxifloxacin

Criteria

Inclusion Criteria:

• Any patients that will be submitted to phacoemulsification surgery in the Hospital de Clinicas of State University of Campinas (BRAZIL)

• Patients over 18 years old

• Patients who are able to perform SD-OCT

• Patients who sign the consent form

Exclusion Criteria:

• Diabetic patients

• Patients with any macular changes prior to the surgery (epiretinal membranes, age macular disease, macular edema...)

• Patients who had any complication during phacoemulsification surgery