Overview

Evaluation of Low-dose Darunavir in a Switch Study

Status:
Completed
Trial end date:
2018-05-16
Target enrollment:
Participant gender:
Summary
This is a switch study to assess the non-inferiority (in terms of efficacy and safety) of darunavir (boosted with ritonavir, DRV/r 400mg/100mg daily) when compared with lopinavir (boosted with ritonavir, LPV/r total dose 800mg/200mg daily), in combination with a nucleoside backbone, administered as a second line therapy in HIV positive individuals.
Phase:
Phase 3
Details
Lead Sponsor:
Willem Daniel Francois Venter
Collaborator:
Medical Research Council, South Africa
Treatments:
Darunavir
Lopinavir
Reverse Transcriptase Inhibitors
Ritonavir