Evaluation of Low Dose Corticosteroids Efficiency, Associated With Myfortic ® in the Treatment of Nephrotic Syndrome
Status:
Completed
Trial end date:
2015-06-01
Target enrollment:
Participant gender:
Summary
A multicenter, randomized, study will be performed to evaluate the efficacy of low dose
steroid combined with mycophenolic acid (MyforticR) versus high dose steroid in inducing
remission in adults with minimal change nephrotic syndrome (MCNS). One hundred and fourteen
patients (CPP decision 2009-04-02-a5) will be included in this study. They will be randomly
assigned to an open label treatment with either prednisone
1 mg/kg/day (arm A) or 0,5 mg/kg/day plus myforticR 1440 mg/day (arm B) for four weeks. The
outcome will be compared during one-year follow up