Evaluation of Etomidate on Adrenal Function in Trauma Patients

• Status: Completed
• Trial end date: 2006-09-01
• Target enrollment: 0
• Participant gender: All

Summary

Trauma patients are at increased risk for adrenal function insufficiency. A commonly used agent for rapid sequence intubation (RSI) is known to decrease adrenal function. We want to determine the incidence of adrenocortical insufficiency and its significance during the first 24 hours of resuscitation following RSI in trauma patients.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Tennessee
• Treatments: Etomidate; Fentanyl; Midazolam; Succinylcholine

Criteria

Inclusion Criteria:

• Trauma mechanism of injury

• Patient requires rapid sequence induction for ventilatory support

Exclusion Criteria:

• <18 years old

• Prisoners

• Pregnant women

• Patients with a history of adrenal insufficiency

• Patients with adrenal trauma documented by CT scan

• Patients receiving corticosteroids in the previous year