Overview Evaluation of Efficacy and Safety of VX-548 for Painful Lumbosacral Radiculopathy (PLSR) Status: Recruiting Trial end date: 2025-04-01 Target enrollment: Participant gender: Summary The purpose of the study is to evaluate the efficacy and safety of VX-548 in treating participants with PLSR. Phase: Phase 2 Details Lead Sponsor: Vertex Pharmaceuticals Incorporated