Evaluation of Effect of Vonoprazan on Midazolam Pharmacokinetics in Healthy Participants
Status:
Completed
Trial end date:
2020-11-25
Target enrollment:
Participant gender:
Summary
To determine the time-dependent inhibition potential of repeated doses of oral vonoprazan on
the pharmacokinetics (PK) of a single oral dose of midazolam, a sensitive cytochrome P450 3A4
(CYP3A4) substrate, in healthy participants.