Evaluation of Dupilumab in Patients With Severe Steroid Dependent Asthma
Status:
Completed
Trial end date:
2017-11-13
Target enrollment:
Participant gender:
Summary
Primary Objective:
To evaluate the efficacy of dupilumab, compared with placebo, for reducing the use of
maintenance oral corticosteroids (OCS) in participants with severe steroid-dependent asthma.
Secondary Objectives:
- To evaluate the safety and tolerability of dupilumab.
- To evaluate the effect of dupilumab in improving participants-reported outcomes.
- To evaluate dupilumab systemic exposure and the incidence of treatment-emergent antidrug
antibodies.