Evaluation of Different Doses of Letrozole in Ectopic Pregnancy

• Status: Completed
• Trial end date: 2022-01-01
• Target enrollment: 0
• Participant gender: Female

Summary

The utilization of letrozole at a daily dose of 10 mg for medical treatment of ectopic pregnancy considerably has a high success rate without imposing any serious side effects compared to daily 5mg letrozole.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Zagazig University
• Treatments: Letrozole

Criteria

Inclusion Criteria:

• Diagnosed ectopic pregnancy was by

• Absence of an intrauterine gestational sac on vaginal ultrasound Coupled with

• β-hCG titers beyond the discrimination zone of at least 2,000 milli-International units (mIU/m).

Exclusion Criteria:

• Patients had contraindications for letrozole

• Patients with any systemic disease ( diabetes, hypertension, ....)

• Patients with b-hCG levels >3,000 mIU/mL

• Patients with hemoglobin level <10 g/dL,

• Patients with platelets count <150,000/mL,

• Patients with elevated liver enzymes,

• Patients with elevated blood urea, or serum creatinine

• The presence of a fetal heartbeat in a gestational sac detected outside the uterine cavity