Overview

Evaluation of Cassia Fistula + Senna Alexandrina Miller in the Chronic Functional Constipation Treatment.

Status:
Completed
Trial end date:
2012-08-01
Target enrollment:
Participant gender:
Summary
Primary Objective: To evaluate the clinical efficacy of Naturetti (capsules) , considering the following criteria: - Evacuation frequency during the treatment and follow-up period - Consistency of stools during the treatment and follow-up period - Global evaluation, regarding increase in frequency of evacuation and shape of stools. Secondary Objective: - Number of days without evacuation - Proportion of evacuation with pain - Proportion of evacuation with strain - Proportion of evacuation with incomplete sensation - Proportion of blocked stools - Proportion of manual maneuvers to facilitate defecation - Proportion of subjects that adhere to the diet recommended - Proportion of the patients who have to use rescue medication - Level of constipation improvement, according to the patient evaluation - To evaluate clinical tolerability of the study medication by the continuous use - To evaluate the occurrence of adverse events related to the study drug - To identify any drug interaction.
Phase:
Phase 3
Details
Lead Sponsor:
Sanofi
Treatments:
Senna Extract
Sennoside A&B