Overview

Evaluation of CAR19 T-cells as an Optimal Bridge to Allogeneic Transplantation

Status:
Active, not recruiting
Trial end date:
2022-03-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to administer novel cluster of differentiation antigen 19 (CD19) specific Chimeric Antigen Receptor T-cells (CAR19 T-cells) to patients with relapsed or resistant Diffuse Large B Cell Lymphoma (DLBCL) to assess the safety and efficacy of this strategy as a bridge to allogeneic transplantation.
Phase:
Phase 1
Details
Lead Sponsor:
University College, London
Treatments:
Cyclophosphamide
Fludarabine
Fludarabine phosphate