Evaluation of Bromocriptine, Metoprolol and Tamsulosin in Eyes With Non-Central DME
Status:
Withdrawn
Trial end date:
2019-05-01
Target enrollment:
Participant gender:
Summary
This phase I/II trial is designed to provide proof of concept evidence that combination
therapy can have a beneficial effect on DME and possibly prevent increases in retinal volume
or progression of non-central DME into the central subfield of the macula. If a beneficial
effect is apparent in this phase I/II study involving a relatively small sample size and
short follow-up period, its results could be used to in plan future phase III trials. We
believe this study will be the first to show that a systems pharmacology approach can
successfully address diabetic macular edema, and thus revolutionize the treatment of complex
retinal diseases for which there are a paucity of effective treatment options.