Overview

Evaluation of Birdshot Retine Choroidopathy Treatment by Either Steroid or Interferon alpha2a

Status:
Completed
Trial end date:
2013-01-01
Target enrollment:
0
Participant gender:
All
Summary
Birdshot Retine choroidopathy (BRC) is a sight threatening posterior uveitis. The long term visual outcome has recently be studied showing a legal blindness to 14% at 5 years. Visual acuity is threatened by macular edema (80%), macular atrophy, and choroidal neovascularization.
Phase:
Phase 2
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Assistance Publique - Hôpitaux de Paris
Treatments:
Interferon alpha-2
Interferon-alpha
Interferons
Prednisone
Criteria
Inclusion Criteria:

- Patients with Birdshot Retine choroidopathy with macular edema

- HLA A29 positive

- Work up of infection or sarcoidosis disease negative

Exclusion Criteria:

- Pregnancy

- Alcohol addiction

- Mood disturbance

- Medullar, hepatic, renal deficiency