Evaluation Montelukast in the Treatment of Status Asthmaticus
Status:
Unknown status
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
The purpose of this study is to evaluate the effectiveness of oral montelukast (Singulair)
given with other standard asthma medications and treatments in the treatment of children with
status asthmaticus. Status asthmaticus is an acute asthma attack that does not respond to
standard intermittent treatments but requires a continuous medication to aid in breathing.
While new medications have been used to better manage chronic asthma, acute asthma
exacerbations continue to be a significant cause of hospitalization and even death in
children. Oral montelukast is a very safe medication that is used to manage chronic asthma in
children, but it has not been studied for use in status asthmaticus. If oral montelukast,
given with other standard therapies, can reduce the treatment length associated with severe,
acute asthma exacerbations in children, it could potentially improve both the morbidity and
burden of pediatric asthma.