Evaluating the Utility of Continuous Positive Airway Pressure in the Treatment of High Altitude Pulmonary Edema

• Status: Recruiting
• Trial end date: 2022-05-01
• Target enrollment: 0
• Participant gender: All

Summary

The primary objective is to evaluate the efficacy of continuous positive pressure on resolution of high-altitude pulmonary edema vs high flow oxygen. The secondary objective is to derive an incidence of high-altitude pulmonary edema based on the elevation and timing from which the subject arrives. Additionally, in a convenience sample of the base study population, an ultrasound evaluation for the presence of B lines in the lungs will be conducted after 2 hours.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Centura Health
• Collaborator: Pulmodyne, Inc.
• Treatments: Nifedipine

Criteria

Inclusion Criteria:

• Male or female, age 18 years or greater

• Oxygen saturation below 85%

• Recent arrival to high altitude

• Dyspnea and cough

• Xray revealing non-cardiogenic pulmonary edema

Exclusion Criteria:

• Pregnancy

• Age below 18

• Patients with respiratory failure requiring intubation

• Patients with altered mental status

• Patients with impaired decision-making capacity

• Patients with a history of congestive heart failure, CAD, COPD, asthma, known current pneumonia

• Extreme facial hair precluding application of CPAP